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SCREENED POSTER

An insight into what SCREENED is about!

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SCREENED BROCHURE

The main challenges in the identification of ED that interfere with the thyroid function and how SCREENED will tackle them !

PUBLICATIONS

2023

CODA: a combo-Seq data analysis workflow; Marta Nazzari et al.; Briefings in Bioinformatics, Volume 24, Issue 1, January 2023, bbac582, https://doi.org/10.1093/bib/bbac582

Investigation of the effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq; Marta Nazzari et al.; Front. Endocrinol., 22 September 2023, Sec. Thyroid Endocrinology, Volume 14 – 2023; https://doi.org/10.3389/fendo.2023.1200211

Clamping strategies for organ-on-a-chip devices; Daniel J. Teixeira Carvalho, Lorenzo Moroni & Stefan Giselbrecht; Nature Reviews Materials Volume 8, pages147–164 (2023); https://doi.org/10.1038/s41578-022-00523-z

Thyroid-on-a-Chip: An Organoid Platform for In Vitro Assessment of Endocrine Disruption; Daniel J. Carvalho et al.; Advanced Healthcare Materials, Volume12, Issue8, March 24, 2023; https://doi.org/10.1002/adhm.202201555

A Computational Template for Three-Dimensional Modeling of the Vascular Scaffold of the Human Thyroid Gland; Giulia Spaletta, et al.; Tissue Engineering Part A, Volume 29, Numbers 1 and 2, 2023; https://doi.org/10.1089/ten.tea.2022.0148

2022

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism; Mírian Romitti, et al; Nature Communications Volume 13, Article number: 7057 (2022); https://doi.org/10.1038/s41467-022-34776-7

Decellularization Detergents As Methodological Variables in Mass Spectrometry of Stromal Matrices; Giulia Remaggi et al.; Tissue Engineering Part C: Methods, Volume 28, Issue 4, April 2022; https://doi.org/10.1089/ten.tec.2021.0191

2020

SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner (project report; download pdf); Lorenzo Moroni, Fulvio Barbaro, Florian Caiment, Orla Coleman, Sabine Costagliola, Giusy Di Conza, Lisa Elviri, Stefan Giselbrecht, Christian Krause, Carlos Mota, Marta Nazzari, Stephen R. Pennington, Annette Ringwald, Monica Sandri, Simon Thomas, James Waddington, Roberto Toni; International Journal of Molecular Sciences, Volume 21, Issue 10 (May 2020).  https://doi.org/10.3390/ijms21103648

LATEST CONFERENCES

2023

12th World Congress (WC12) on Alternatives and Animal Use in the Life Sciences, 27-31 August 2023, Niagara Falls, Canada: SCREENED was represented at this event and Daniel Carvalho from project partner Maastricht University presented a poster on Thyroid organoid-on-a-chip batteries for screening endocrine disruption.

World Summit MPS 2023, 26-30 June 2023, Berlin, Germany: SCREENED actively participated in the conference and presented project results in a talk held by Daniel Carvalho from Maastricht University, with the following title: Thyroid-on-a-chip: an In Vitro Organoid Device to Test Thyroid Disruption.

ENDO2023, 15-18 June 2023, Chicago, USA: SCREENED partner Université libre de Bruxelles had the privilege to be invited to this conference to hold a talk on the Emerging technologies to model the thyroid.

EURION Annual Meeting, 20-21 January 2023, VU Amsterdam, Netherlands: As partner of the European Cluster to improve identification of endocrine disrupters, SCREENED was represented by several project partners and actively contributed with a highlight presentation on the latest results of the project, given by Project Coordinator Lorenzo Moroni (Maastricht University), as well as with two posters:

  • H2020 SCREENED: Modelling the alteration of thyroid function on exposure to chemicals, by Prakash Patel, Cyprotex.
  • Investigation of the epigenetic effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq, by Marta Nazzari, Maastricht University. This poster was also selected for a spotlight presentation.

 32nd Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 20-23 September 2023, Venice, Italy: At this event, a keynote lecture on Innovations from the Horizon 2020 European SCREENED project: iron-doped hydroxyapatite nanoparticles (FeHA NPs) for magnetic guidance of rat thyrocytes onto thyroid lobe-like 3D collagen scaffolds was given by Roberto Toni from SCREENED partner Parma University.

PRESS RELEASES

SCREENED PROJECT LAUNCH (January 2019)

 

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